Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Aralen ancestral tomb Purifying chloroquine phospahte Rheumatoid arthritis guidelines hydroxychloroquine Ocular Surgery News The American Academy of Ophthalmology has published several dosing and screening recommendations for hydroxychloroquine to avoid potential retinal toxicity, yet some patients. My Take on New Ocular Screening Guidelines for Plaquenil By Sergio Schwartzman, MD 14 October 2016 A recent article published by the American Academy of Ophthalmology AAO presented new recommendations for screening of patients being managed with hydroxychloroquine HCQ. Dr. Corte provides a quick reference guide based on the AAO's updated screening guidelines for chloroquine and hydroxychloroquine Plaquenil retinopathy. As optometrists, it is important that we are aware of the possible ocular complications that can occur from the use of high risk medications. While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Screening criteria for ocular toxicity of plaquenil New Screening Guidelines for Hydroxychloroquine Toxicity, My Take on New Ocular Screening Guidelines for Plaquenil RheumNow. Hydroxychloroquine and weight gainChloroquine phosphate tablets 500mg Periodic eye exams in patients taking HCQ is to recognize toxicity, if it occurs, at the earliest 17 possible stage. Toward this end, the American Academy of Ophthalmology AAO has 18 published guidelines for retinal toxicity monitoring 4, 5. 19 AMERICAN COLLEGE OF RHEUMATOLOGY. Quick Reference Screening for Chloroquine.. PowerPoint. Update on Plaquenil Testing. Eye care specialists provide a valuable service when screening for Plaquenil retinal toxicity and advising the treating physician or rheumatologist with regards to the patient’s risk, safe dosing and appropriate screening procedures. Although it is considered rare, retinal toxicity from the intake of Plaquenil can be irreversible even if the drug is discontinued 2, 3. What is Plaquenil Toxicity? The toxicity resulting from the intake of Plaquenil is due to its affinity for melanin-containing structures in the body. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1is now considered for new disease applications in diabetes, heart disease and adjunct.