It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Ciprofloxacin and hydroxychloroquine Hydroxychloroquine sun allergy What otc meds can be taken with plaquenil Do not take this medicine in larger or smaller amounts or for longer than recommended. Plaquenil is sometimes given only once per week. Choose the same day each week to take this medicine if you are on a weekly dosing schedule. Take Plaquenil with a meal or a glass of milk. To prevent malaria Start taking Plaquenil 2 weeks before entering an area where malaria is common. Continue taking the medicine regularly during your stay and for at least 8 weeks after you leave the area. Ok I'll admit I'm impatient to feel better and get on with my life. My question is, how long does it take for plaquenil to make an impact? And does it really help the fatigue? That's my biggest issue. I've been on it for about three and a half weeks. Thanks! Danni How long did it take for Plaquenil to work? I'm just curious how long it took everyone to start to notice a different. My dr said it would take 6-12 weeks to start to notice anything but I only started Plaquenil 3 weeks ago and I swear I can already notice a difference. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. How long plaquenil take to work Plaquenil - does it take long time to work? - Lupus - Inspire, When does the plaquenil kick in? DailyStrength What is chloroquine injectionChloroquin functional groupsPlaquenil ful fielderg severe The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. Taking Plaquenil for Rheumatoid Arthritis. How long did it take for Plaquenil to work? lupus. Lupus Board Index how long does it take plaquenil to work. How long is it supposed to it take for plaquenil hydroxychloroquine to get rid of the lupus butterfly rash? 1 doctor responded I had a skin rash from plaquenil hydroxychloroquine. It took me about 9 or 10 months. When I developed a severe flare, my rheumy started me on prednisone and plaquenil at the same time. This way while I tapered off the pred over 8 months, the plaquenil was building up in my system. 4 replies How long did Plaquenil take to work for you? My Dr said it would take 3 months! My Dr said it would take 3 months! However, I read that it took less time for some people.