Literature review of chloroquine syrup

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    Literature review of chloroquine syrup


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. Approved indication: For the suppressive treatment of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: 300 mg base (500 mg salt) orally once a week Comments: -For prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas.

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    Chloroquine cardiomyopathy – a review of the literature Ernst Tönnesmann Department of Internal Medicine, Kaiser-Karl-Klinik BonnGermany Correspondence [email protected], Reinhard Kandolf Institute for Pathology, University Hospital Tübingen TübingenGermany & Thorsten Lewalter Isar Heart Center Munich MunichGermany A bibliometric review of drug repurposing provides novel insights into the practice. • Some drugs have been tried in hundreds of diseases. • Even an old drug like chloroquine is actively being tested in new therapeutic applications. ABSTRACTMalaria is an enormous public health problem worldwide and kills one to two million people every year, mostly children residing in Africa. And the aim of this study is to determine the impact of combined treatment with Artesunate and Chloroquine on the white blood cell count of plasmodium berghei infected albino mice. And to compare and observe effect of combined treatment of.

    Approved indication: For acute attacks of malaria due to P vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: Chloroquine-sensitive uncomplicated malaria (Plasmodium species or species not identified): 600 mg base (1 g salt) orally at once, followed by 300 mg base (500 mg salt) orally at 6, 24, and 48 hours Total dose: 1.5 g base (2.5 g salt) Comments: -For the treatment of uncomplicated malaria due to chloroquine-sensitive P vivax or P ovale, concomitant treatment with primaquine phosphate is recommended. 60 kg or more: 1 g chloroquine phosphate (600 mg base) orally as an initial dose, followed by 500 mg chloroquine phosphate (300 mg base) orally after 6 to 8 hours, then 500 mg chloroquine phosphate (300 mg base) orally once a day on the next 2 consecutive days Total dose: 2.5 g chloroquine phosphate (1.5 g base) in 3 days Less than 60 kg: First dose: 16.7 mg chloroquine phosphate/kg (10 mg base/kg) orally Second dose (6 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Third dose (24 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Fourth dose (36 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Total dose: 41.7 mg chloroquine phosphate/kg (25 mg base/kg) in 3 days Comments: -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of malaria due to P vivax and P malariae.

    Literature review of chloroquine syrup

    Chloroquine hydrochloride Semantic Scholar, A bibliometric review of drug repurposing - ScienceDirect

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  6. Adherence to clinic‐prescribed antimalarial drugs. Thirteen studies gave details of adherence to antimalarial drug regimes prescribed in clinics prior to any intervention either as purely descriptive studies n = 3, as a baseline in intervention studies n = 5, or as part of a clinical effectiveness study n = 5.

    • How do patients use antimalarial drugs? A review of the..
    • EFFECT OF COMBINED TREATMENT WITH CHLOROQUINE AND..
    • Chloroquine drug Britannica.

    Ansah et al. 2001 conducted an RCT of chloroquine tablets for children compared to chloroquine syrup, while Denis et al. 1998 evaluated videos and posters as community health education strategies to improve adherence to a 7-day regimen of quinine + tetracycline. Chloroquine phosphate has been reported to be a valuable alternative therapy for cutaneous lesions of sarcoidosis. With a judiciously determined daily dosage and regular 6-month ophthalmologic follow-up examinations, the risk of developing retinopathy can be avoided, because the daily dosage rate rather than total dose accumulation determines the development of chloroquine-induced retinopathy. Systematic review of the extent of chloroquine resistant P. vivax and the different methodologies used to quantify therapeutic efficacy. One of the major threats to malaria control and elimination efforts is the ongoing spread and emergence of resistance towards commonly used antimalarial drugs to treat P. falciparum and P. vivax infections.

     
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    Targeting endosomal acidification by chloroquine analogs as a. Jan 23, 2017 The increasing evidence suggests that the entry, replication and infection processes of several viruses such as Ebola, Marburg, dengue, Chikungunya, HIV etc. are highly dependent on endosomal‐lysosomal acidification and the activities of several host endosomal proteases ‐ which are also active in acidic pH environments Sun and Tien 2012; Barrow et al. 2013.

    Chloroquine - an overview ScienceDirect Topics