Plasmodium species are transmitted by the bite of an infective female mosquito. Occasionally, transmission occurs by blood transfusion, organ transplantation, needle sharing, nosocomially, or from mother to fetus. Turmeric and hydroxychloroquine Chloroquine phosphate dosage aquarium Chloroquine is used extensively in malaria endemic areas in Africa to treat the uncomplicated form of Plasmodium falciparum malaria. However, the efficiency of chloroquine has been severely impacted by the recent development of chloroquine resistant plasmodium falciparum parasites. ANSWER Chloroquine-resistant malaria has been observed in India and so the first line drug of choice should be an artemisinin-derivative in combination with another drug this group of medications are more generally known as "artemisinin-based combination therapies" or ACTs. In addition, physicians treating malaria acquired in Haiti should be aware of the possibility of chloroquine-resistant infections. Patients with persistent fever despite treatment and infected travelers reporting adherence to chloroquine prophylaxis should be treated with alternate antimalarial drug therapy. Travelers going to malaria-endemic countries are at risk for contracting the disease, and almost all of the approximately 1,700 cases per year of malaria in the United States are imported. Malaria is a major international public health problem; 91 countries reported an estimated 216 million infections and 445,000 deaths in 2016, according to the World Health Organization (WHO) World Malaria Report 2017. Chloroquine resistant malaria Chloroquine Dosage Guide with Precautions -, Chloroquine-Resistant Malaria – Plaquenil for oaPlaquenil dr mercolaChloroquine protein degradation Chloroquine used to be taken daily in many of the tropical Britain colonies suffering from malaria. chloroquine in the form of quinine is where the gin and tonic drink came from. Quinine mixed with carbonated water was drunk as a prophylactic. The quinine tasted so terrible it had to be cut with something to make it tolerable - gin! Chloroquine has shown apparent efficacy in treatment of.. Chloroquine-Resistant Malaria in Travelers Returning from.. Coronavirus cure All you need to know about anti-malaria.. This deficiency explains the reduced ability of chloroquine-resistant parasites to concentrate chloroquine, and it suggests that chloroquine resistance is due to a decrease in the number, affinity, or accessibility of chloroquine receptor sites on a constituent of the malaria parasite. Mefloquine is one of the oldest chloroquine-resistant falciparum Malaria pills developed during the Vietnam War. It is taken weekly starting the week before you arrive in the risk area, and for four weeks after leaving the area. However, Mefloquine is not often prescribed by travel doctors because of its side effects. Quinine remains an important and effective treatment for malaria today, despite sporadic observations of quinine resistance. 1 Chloroquine. Research by German scientists to discover a substitute for quinine led to the synthesis in 1934 of Resochin chloroquine and Sontochin 3-methyl-chloroquine.