About 5-30% of autoimmune patients are inclined to develop additional autoimmune diseases leading to the development of overlap diseases. An overlap between Lupus and Rheumatoid Arthritis (RA) referred to as Rhupus has been much on debate, whether it represents a single distinct entity or an overlap disease? du Montcel ST, Michou L, Petit-Teixeira E, Osorio J, Lemaire I, Lasbleiz S et al. Korendowych E, Owen P, Ravindran J, Carmichael C, Mc Hugh N. Orozco G, Eyre S, Hinks A, Bowes J, Morgan AW, Wilson AG et al. New guidelines for plaquenil macuopathy 2018 pubmed Plaquenil lyme cysts Plaquenil staggered dose Does hydroxychloroquine cause hair loss Plaquenil Hydroxychloroquine. The drug of choice for systemic lupus erythematosus SLE or "Lupus" and rheumatoid arthritis. Hydroxychloroquine is a one of a number of drugs which have been used for many years in the treatment of malaria. Fortunately, it was discovered these drugs often are helpful in the treatment of various rheumatic diseases. Description and Brand Names. Drug information provided by IBM Micromedex US Brand Name. Plaquenil; Descriptions. Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work. Plaquenil is also known by its drug name, Hydroxychloroquine. Plaquenil may be prescribed at a low dose for maintenance, or at a high dose to control acute flare-ups. Plaquenil is a disease-modifying drug originally developed to treat malaria. Plaquenil is believed to work by interfering in communication between the cells of the immune system. Discussion Rhupus is known to be a complex musculoskeletal autoimmune disease defined by erosive polyarthritis. Herein we reviewed the literature over the past 54 years to characterise rhupus subjects and to support the theory of overlap. HLA class II association with rheumatoid arthritis: facts and interpretations. New classification of HLA-DRB1 alleles supports the shared epitope hypothesis of rheumatoid arthritis susceptibility. The clinical and genetic associations of anti-cyclic citrullinated peptide antibodies in psoriatic arthritis. Study of the common genetic background for rheumatoid arthritis and systemic lupus erythematosus. Does plaquenil treat rhupus Hydroxychloroquine Plaquenil Side Effects & Dosage for., Hydroxychloroquine Oral Route Description and Brand. Plaquenil and orthopedic surgery Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine Plaquenil. Plaquenil Hydroxychloroquine MyLupusTeam. RA and Hydroxychloroquine How Effective is it for.. Today, Plaquenil and other antimalarials are also used to treat and help prevent symptoms caused by certain autoimmune diseases such as rheumatoid arthritis RA, systemic lupus erythematosus, and discoid lupus, even though these diseases are not caused by malaria parasites. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. Generally, Plaquenil is a treatment option as monotherapy used alone for mild rheumatoid arthritis or as combination therapy with other DMARDs for moderate to severe disease.