It leads to fluid buildup, especially in your legs. Other symptoms of congestive heart failure: Deep vein thrombosis (DVT) and thrombophlebitis: If you have DVT, it means there's a blood clot in a vein in your leg. When that happens, it's called a pulmonary embolism, and it can be life-threatening. Can you buy chloroquine over the counter Plaquenil retinal deposits Lupus arthritis causes pain, stiffness, swelling, tenderness and warmth in your joints. The joints most often affected are the ones farthest from the middle of the body, such as fingers, wrists, elbows, knees, ankles and toes. General stiffness upon awakening, which gradually improves as the day goes on, is a key feature of lupus arthritis. Jan 11, 2018 Leg swelling related to fluid buildup Leg swelling caused by the retention of fluid in leg tissues is known as peripheral edema. It can be caused by a problem with the circulatory system, the lymphatic system or the kidneys. Leg swelling isn't always a sign of a heart or circulation problem. People with myositis caused by a virus usually have symptoms of a viral infection, such as runny nose, fever, cough and sore throat, or nausea and diarrhea. But the symptoms of viral infection may go away days or weeks before myositis symptoms begin. Some people with myositis have muscle pain, but many do not. One of the first symptoms of DVT or thrombophlebitis is one swollen leg (especially the calf), as blood pools in the area. In thrombophlebitis, also called superficial thrombophlebitis, clots form closer to the surface of the skin and aren't likely to break off. Plaquenil leg swelling Taking Plaquenil for Rheumatoid Arthritis, Leg swelling Causes - Mayo Clinic Plaquenil and heart rate Nov 28, 2018 Heavy legs and edema in the ankles occur due to vascular insufficiency. Monitor your diet and eliminate salt when possible. This leads to swelling in the ankles and high-blood pressure. Keeping your legs above your heart helps maintain the flow of venous blood. Heavy legs and edema may be secondary to another illness such as diabetes. How to Avoid Having Heavy Legs & Swelling of Ankles Healthfully. Myositis Symptoms and Causes - WebMD. What Are the Causes of Unilateral Upper Limb Edema.. When the left ankle swelledup, it is the one with the worst vitiligo hyperpigment and lump, and the left side of my heart had some atrophy that my recent cardiologist could not find, though I have an irregular heart beat on the left side, off the plaquenil, my leg very nearly turned blue when it swelled and it was cold. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Plaquenil and Swelling - from FDA reports Summary Swelling is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Osteoporosis.