Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Can plaquenil cause ear problems Hydroxychloroquine cancer treatment Also if your doing more exercise, it will also bring down your sugar much quicker. After exercising have some Orange juice, and a Carb. My sugar has lately been swinging both ways very quickly. Very high, and then after exercise to very low. Not able to control mine by diet, any more. Gastro doctor wants me on insulin. Hugs So back to the Sjogren's World Forums participant this person noticed that after beginning to take Plaquenil, it became more difficult to keep her diabetes in control occasionally her blood sugar became too low and she had symptoms of hypoglycemia feeling very anxious, tremor, feeling suddenly very hungry, perspiring heavily, and feeling faint. Several others chimed in, many of whom were not diabetic, and said that they noticed the same thing. I've been on Plaquenil for a little over a year and it definitely does drop my blood sugar. It's actually in the medicine's literature that it can do this. I'm not diabetic and I normally run low normal blood sugar. However, on this medication, I have episodes of hypoglycemia. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Can plaquenil cause low blood sugar Plaquenil and low wbc - Things You Didn’t Know, Reasonably Well Plaquenil and Hypoglycemia Ic hydroxychloroquinePlaquenil and oxycodoneHow many people taking hydroxychloroquine Plaquenil does lower blood sugar. I found that out shortly after I began taking it. And from my endocrinologist. Please eat a healthy diet, frequent small meals throughout the day, and make sure you have an adequate protein to carbohydrate ratio in your meals. I always make sure I have yogurt on hand just in case my sugar dips too low. Plaquenil and low blood sugar - Sjogren's World. Plaquenil and hypoglycemia. A favorable effect of hydroxychloroquine on glucose and.. There was one ER dr. at Mayo Clinic who mentioned to me when I had gone there during a bad tachycardic episode, that Plaquenil can be a drug that can be a cause of that. When I followed up with Rheum and pcp, of course they all just dismissed any of that. Hypoglycaemia and hydroxychloroquine. This might seem a bit of a an odd question, but has anybody on hydroxychloroquine plaquenil experienced low blood sugar episodes after eating? I've just seen it can be a side effect and I've been getting shaky and jittery after eating, especially something sugary. You have experienced low blood sugar levels hypoglycaemia - a "hypo". Plaquenil may increase the risk of you having a hypo.