It is estimated that as many as 8 million people in Mexico, Central America, and South America have Chagas disease, most of whom do not know they are infected. If untreated, infection is lifelong and can be life threatening. Aralen malaria medication How does chloroquine phosphate work Treatment for Chagas disease is recommended for people diagnosed early in the course of infection acute phase, babies with congenital infection, and for those with suppressed immune systems. Many patients with chronic infection may also benefit from treatment. Patients should consult with their primary health-care provider. In tropical regions, protozoan parasites can cause severe diseases with malaria, leishmaniasis, sleeping sickness, and Chagas disease standing in the forefront. Many of the drugs currently being used to treat these diseases have been developed more than 50 years ago and can cause severe adverse effects. This chapter discusses Chagas' disease. Trypanosoma cruzi, which is the protozoan parasite causing Chagas' disease, represents the most significant health problem in the American continent in terms of human health, socioeconomic impact, and geographic distribution. This parasite also affects a large number of mammalian species. Large-scale population movements from rural to urban areas of Latin America and to other regions of the world have increased the geographic distribution and changed the epidemiology of Chagas disease. The impact of Chagas disease is not limited to only rural areas of Latin America in which vectorborne transmission (diseases transmitted by insects) occurs. Chagas disease is treated with chloroquine t f Prescription drugs used to treat protozoal intestinal., Agrochemicals against Malaria, Sleeping Sickness. Hydroxychloroquine and menstrual cyclePlaquenil dental contraindicationsPlasmodium falciparum resistance to chloroquinePlaquenil color vision effectsHydroxychloroquine sulfate tablets usp 200 mg side effects Two drugs can treat the disease benznidazole Alunbrig and nifurtimox Lampit, which kill the parasite. They work well if taken soon after infection. The longer someone's had Chagas disease, the less likely the drugs are to work. Pregnant women can’t take them, but infected newborns can. What is the treatment for Chagas disease?. Chagas' Disease American Trypanosomiasis - ScienceDirect. WHO Treatment of Chagas disease. A retrospective follow-up study was also conducted to determine the safety of benznidazole by reviewing the medical records of 224 adults with chronic Chagas disease treated with the drug. The analysis showed that adverse events occurred in 205 cases 91.5% and that 52 of these cases 23.2% required stopping benznidazole treatment. Chagas disease is an infectious disease caused by the Trypanosoma cruzi T. cruzi parasite. Since the bug that transmits it lives in Central America, South America, and Mexico, this is where the vast majority of infections are seen, though some cases were recently found in the southern United States. Chagas disease can cause a sudden, brief illness acute, or it may be a long-lasting chronic condition. Symptoms range from mild to severe, although many people don't experience symptoms until the chronic stage. Acute phase. The acute phase of Chagas disease, which lasts for weeks or months, is often symptom-free.