While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. "I started the hydroxychloroquine medication a week ago and within the first day or two noticed a big difference in my pain and fatigue with major improvement SLE. Plaquenil for lupus mechanism Chloroquine injection side effects Chloroquine lysosome sigma Medicine for lupus plaquenil Lupus and Plaquenil research. While Plaquenil was not created with the explicit purpose of helping people minimize the disease activity of lupus, a number of clinical trials have been conducted to examine the clinical impact of the medication. The incidence of new-onset or flaring psoriasis associated with Plaquenil varies from 0-100% depending on which case series report you read! Allergic and psoriasis-like rashes tend to develop within the first few weeks or months of starting Plaquenil. If Plaquenil helps a serious chronic disease such as lupus, it may be taken for years. Weight-bearing exercise forces you to work against gravity, placing stress on the bones. Autoimmune diseases, like rheumatoid arthritis and lupus, are linked. Facts for patients and caregivers about the DMARD drug Hydroxychloroquine Plaquenil such as usages, Today, it is used to treat rheumatoid arthritis, It can decrease the pain and swelling of arthritis. Hydroxychloroquine (Plaquenil) is considered a disease-modifying anti-rheumatic drug (DMARD). What if plaquenil doesn't work for lupus Hydroxychloroquine User Reviews for Systemic Lupus., Plaquenil Use in Autoimmune Diseases Plaquenil treatment rheumatoid arthritisRa treatment hydroxychloroquineChloroquine ovarian cancerHydroxychloroquine tab Oct 22, 2009 There are pros and cons for all of them and it's a matter of finding one that suits and one that doesn't give you any intolerable side effects. Make sure you take them on a full stomach. Your doc would help you work out which one might be best for you based on your individual circumstances. Good luck! If Plaquenil doesn't work. Lupus Forums at The Lupus Site. How Does Plaquenil Work For Rheumatoid Arthritis. What next if plaquenil doesn't work? -. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. No fetal abnormalities are known to have occurred from taking hydroxychloroquine, and physicians at several major universities have used anti-malarial drugs for years to treat pregnant women with lupus without negative side effects on the fetus. How to use Plaquenil. Lupus and/or rheumatoid arthritis patients will most likely take this medication by mouth, usually once or twice daily or as directed. Hydroxychloroquine generally is given to adults in doses of 200 mg or 400 mg per day. In some cases, higher doses can be used.