The clinical trials on this list are studying Hydroxychloroquine. NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. Plaquenil effects menstrual cycle Chloroquine stability Ankylosing spondylitis hydroxychloroquine Plaquenil copay cards Hydroxychloroquine in Previously Treated Patients With Metastatic Pancreatic Cancer Hydroxychloroquine is approved for the treatment of non-cancerous illnesses such as rheumatoid arthritis and systemic lupus erythematous. Researchers in the laboratory have tested tumors from patients with pancreatic cancer and have discovered that they have certain pathways inside the cells that promote growth and survival of the tumor. One of the treatments for small cell lung cancer SCLC is chemotherapy. The chemotherapy most often used is a carboplatin and etoposide. This is a standard treatment. Recent research shows that a drug called hydroxychloroquine HCQ might help chemotherapy work better. Hydroxychloroquine and Gefitinib to Treat Lung Cancer. Non-small cell lung cancer NSCLC is the most common cause of cancer mortality in men and women in Singapore. Chemotherapy and biologically targeted agents can extend survival only modestly for these patients; therefore, discovery of novel ways to prolong the disease course is a top research. Talk to your doctor for help in deciding if one is right for you. You may want to think about taking part in a clinical trial. Hydroxychloroquine and lung cancer Hydroxychloroquine and Gefitinib to Treat Lung Cancer., A trial of chemotherapy and hydroxychloroquine for small. Plaquenil and thrombocytopeniaCan plaquenil be used with humiraPlaquenil and numb tingling handsPlaquenil total doseHydroxychloroquine off label uses As a lysosomotropic agent, hydroxychloroquine raises intralysosomal pH, impairing autophagic protein degradation; hydroxychloroquine-mediated accumulation of ineffective autophagosomes may result in cell death in tumor cells reliant on autophagy for survival. NCI Drug Dictionary - National Cancer Institute. Hydroxychloroquine and Gefitinib to Treat Lung Cancer - genglob magazine. Repurposing Drugs 101 - Chloroquine & Lung Cancer. Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Hydroxychloroquine Plaquenil is also a disease-modifying anti-rheumatic drug DMARD used to treat both acute and chronic rheumatoid arthritis, systemic lupus erythematosus, and discoid lupus erythematosus. Lung cancer. The combination of HCQ with erlotinib can be used safely in daily doses of 150 mg erlotinib and 1000 mg HCQ, as determined by a phase-1 study in 27 patients with advanced non-small cell lung cancer NSCLC. Of the 19 patients who remained in the study, one had a partial response and four had stable disease as best response.