It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Chloroquine dosage sle Hydroxychloroquine sulphate tablets usp The risk of a toxicity sharply increases after 5 years, with majority of cases of retinotoxicity occurring in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine Plaquenil. This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day 200 bid. Mg 310-465 mg base PO daily for 4-12 weeks; maintenance 200-400 mg 155-310 mg base PO daily. For individuals with significant risk factors daily dose of hydroxychloroquine sulfate 5.0 mg/kg base of actual body weight, subnormal glomerular filtration, use of tamoxifen citrate or concurrent macular disease monitoring should. Plaquenil comes in 200 milligram mg tablets that are taken by mouth. To prevent malaria in adults, two tablets are typically taken once a week, on the same day each week. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Plaquenil 400 mg daily Hydroxychloroquine Plaquenil - RA Daily Blog, Experts., Plaquenil hydroxychloroquine sulfate dosing, indications. Hydroxychloroquine swollen lymph nodesTreatment of chloroquine resistant falciparum malariaPlaquenil macular degenerationHypoglycemia plaquenil I was on 400 mg of plaquenil 2 years ago when i was first diagnosed as well as prednisone. When she took me off the plaquenil, I definately could feel a difference, a lot of pain returned. I am on it again now for about a year and I have no side effects from it. I do have to have my eyes checked once a year though. Plaquenil DailyStrength. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Hydroxychloroquine - LiverTox - NCBI Bookshelf. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. your doctor may lower your dosage to 200–400 mg per day, as a single daily dose or in two divided doses. One of the most serious side effects is a toxicity in the eye generally with chronic use.11 People taking 400 mg of hydroxychloroquine or less per day generally have a negligible risk of macular toxicity, whereas the risk begins to go up when a person takes the medication over 5 years or has a cumulative dose of more than 1000 grams. Systemic lupus erythematosus is treated with 400 mg once or twice daily for several weeks then 200-400 mg daily. Hydroxychloroquine should be taken with food or milk in order to reduce stomach upset.