Most importantly, you help support continued development of this site. The majority of cases of retinotoxicity have occurred in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine (Plaquenil). This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day (200 bid). How does hydroxychloroquine treat lupus What is plaquenil taken for Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes. A recent large study of people with cardiovascular disease found that hydroxychloroquine Plaquenil does not increase the risk of infection and methotrexate increases the risk of infection only slightly. The concern with immune suppression is that the virus could replicate more freely and cause more severe or extensive disease, says Dr. Winthrop. Unlike many meds used to treat autoimmune diseases immune modulators that suppress the immune system Plaquenil hydroxychloroquine has an antiinflammatory effect on autoimmune dss. So the risk of infections seen with immune suppression is uncommon. Major concern with this drug is effect on vision. It now solely uses real body weight (rather than ideal body weight) based on new recommendations from a 2014 study (1). Disclaimer: This tool is designed to help eye care professionals better understand the risk the of retinotoxicity from hydroxychloroquine. Please note: This calculator was modified in 9/2015. Plaquenil and infection risk Hydroxychloroquine Plaquenil, Coronavirus and Arthritis What You Need to Know. Can you take hydroxychloroquine with methotrexateWhat should you test for with hydroxychloroquine Sep 13, 2016 A key concern for patients with lupus is the risk of infections including serious infections with immunosuppressive drugs and glucocorticoids, since both treatments suppress the immune system 5–7. This concern likely plays a significant role in a patient’s decision regarding whether to take these medications, and how long to continue treatment, sometimes despite a strong physician recommendation. Risk of serious infections with immunosuppressive drugs and.. Can plaquenil hydroxychloroquine for autoimmune disease.. PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION. First, the yeast infection is not a complication of Plaquenil rather it is due to Sjogren's in which yeast infections are common and Plaquenil reduces the risk of yeast infection in such patient. Now about the drug interaction of Plaquenil and Diflucan, an FDA study done shows that there takes place an interaction between these two drugs by causing the effect on the heart. Apr 10, 2019 Before using Plaquenil, tell your doctor if you are allergic to any drugs, or if you have psoriasis, porphyria, liver disease, alcoholism, or glucose-6-phosphate dehydrogenase G-6-PD deficiency. Take Plaquenil for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. Infection is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Pain.