It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Chloroquine rheumatoid arthritis mechanism of action Plaquenil for pmle Lastly, a drug that is related to plaquenil called quinacrine may be helpful to take. This has lower incidence of retinal toxicity than plaquenil, but has other unique side effects that need to be monitored. Sue, I took mine breakfast & supper, to space them out. I bought a pill case for my handbag that's shaped like a pill capsule, as a graphic reminder to place by my plate. Had someone in a restaurant thinking it was a real pill once. Pretty funny, as it's huge. Hope the med kicks in for you well. Best wishes, from Vee Binding of the drug to melanin in the RPE contributes to, or prolongs, its toxic effects. 2. Plaquenil toxicity is typically asymptomatic in early stages, but over time can lead to severe vision loss and retinal damage. For prolonged treatment of lupus or arthritis, adverse effects include the acute symptoms, plus altered eye pigmentation, acne, anaemia, bleaching of hair, blisters in mouth and eyes, blood disorders, convulsions, vision difficulties, diminished reflexes, emotional changes, excessive coloring of the skin, hearing loss, hives, itching, liver problems or liver failure, loss of hair, muscle paralysis, weakness or atrophy, nightmares, psoriasis, reading difficulties, tinnitus, skin inflammation and scaling, skin rash, vertigo, weight loss, and occasionally urinary incontinence. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. For short-term treatment of acute malaria, adverse effects can include abdominal cramps, diarrhea, heart problems, reduced appetite, headache, nausea and vomiting. Plaquenil pill shape Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria, Immune & Autoimmune - Lupus Plaquenil - when to take the 2. Natural alternatives for plaquenilPlaquenil itching remedy Hydroxychloroquine sulfate greater than 6.5 mg/kg 5 mg/kg base of actual body weight, durations of use greater than five years, subnormal glomerular filtration, use of some concomitant drug products such as tamoxifen citrate and concurrent macular disease. PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION. How to Succeed in Plaquenil Screenings. Plaquenil - Side Effects, Uses, Dosage, Overdose, Pregnancy.. Plaquenil Oral tablet 200mg Drug Medication Dosage information. Learn about the reported side effects, related class drugs, and how these medications will affect your daily lifestyle. Plaquenil hydroxychloroquine is an antimalarial medication used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so.