It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Does plaquenil reduce rheumatoid factor in patiences with sjogrens Hydroxychloroquine lupus nephritis Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Methotrexate vs plaquenil side effects long term and short term. I was recently diagnosed with an autoimmune disease that mainly fuses my joints together, but causes severe pain and fatigue. The only problem is the Plaquenil causes severe headaches that interfer with my daily activities also. It may take several weeks or months to see improvement if you are taking this for lupus or arthritis. Hydroxychloroquine may not prevent malaria in all cases. Hydroxychloroquine may not prevent. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Can plaquenil be taken long term Rx Side Effects New Plaquenil Guidelines and More., Methotrexate vs plaquenil side effects long term and short. Hydroxychloroquine medline plus Feb 20, 2018 Plaquenil is taken by mouth with food or milk to prevent stomach problems. When taking this medication, some patients may experience upset stomach, nausea, loss of appetite, headaches or dizziness. Sometimes, taking high doses or long-term treatment of Plaquenil can lead to vision problems. Focus on Eyes Long-term Plaquenil intake can affect your vision. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Plaquenil Hydroxychloroquine MyPsoriasisTeam. The study concludes that hydroxychloroquine therapy is safe for long-term use at doses 5 mg/kg/day. Learn about how lupus affects the eyes and hydroxychloroquine. See More Hydroxychloroquine comes as a tablet to take by mouth. For prevention of malaria in adults, two tablets are usually taken once a week on exactly the same day of each week. The first dose is taken 1 to 2 weeks before traveling to an area where malaria is common, and then doses are continued for 8 weeks after exposure. Aug 14, 2017 Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA.