Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Chloroquine phosphate solubility storage Plaquenil and glaucoma Table 1. Effect of NSAIDs, immunosuppressive drugs, and biologic agents on male and female fertility* Drug Effect NSAIDs Females May inhibit ovulation Males No inﬂuence on spermatogenesis Chloroquine, hydroxychloroquine Does not impair fertility in males or females Sulfasalazine Females No inﬂuence on fertility INTRODUCTION There is a high prevalence of methotrexate MTX use in males of reproductive age. The scope of this paper reviews what is known regarding risks to fertility and partners' pregnancy outcomes with regard to MTX use in men. Fertility Animal studies showed an impairment of male fertility with chloroquine treatment see TOXICOLOGY, Reproductive and development toxicity. There are no data in humans. Special Populations Pregnancy Hydroxychloroquine crosses the placenta. Data are limited regarding the use of PLAQUENIL during pregnancy. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine male fertility Will you have Infertility with Plaquenil - eHealthMe, The toxicity of methotrexate in male fertility and. Chloroquine gram negative or positivePlaquenil fda pregnancy categoryEasy bruising plaquenil Azathioprine treatment and male fertility in inflammatory bowel disease. Preliminary results presented at Digestive Disease Week, Orlando, Florida, May 1999, and at the 7th United European Gastroenterology Week Poster of Distinction, Rome, Italy, November 1999. Azathioprine treatment and male fertility in inflammatory.. Plaquenil Hydroxychloroquine Sulfate - Sanofi. Hydroxychloroquine Oral Route Description and Brand.. Hydroxychloroquine can aggravate pre-existing psoriasis. Does hydroxychloroquine affect fertility or pregnancy? Hydroxychloroquine must be avoided during pregnancy as it may harm the unborn child. If you are planning a family, or wish to breast feed, you should seek advice from your doctor. Dermatological reactions to hydroxychloroquine sulfate tablets may occur. It is not recommended for the treatment of psoriasis or porphyria as these conditions may be exacerbated by its use. Observe caution in patients with psoriasis. Sexual Health Fertility Animal studies showed an impairment of male fertility with chloroquine treatment see Rheumatoid arthritis RA is a lifelong, systemic autoimmune disease. Immune system does not work properly in rheumatoid arthritis and start attacking healthy tissues – joints that typically results in warm, swollen Pic. 1, and pain of joints. The disease may also affect other parts of the body.