Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Night swets plaquenil Plaquenil hair loss Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. The aforementioned rare side effect that affects vision hydroxychloroquine retinopathy, if caught early, may improve after discontinuation of Plaquenil. Since the side effect of vision loss is possible but rare, it is important for you to tell your doctor about any vision changes that you experience. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. How soon would you have side effects with plaquenil Hydroxychloroquine Oral Route Side Effects - Mayo Clinic, Plaquenil Side Effects on Your Eyes and Vision Plaquenil lichen planusHow to take plaquenil without getting nauseous Plaquenil received an overall rating of 5 out of 10 stars from 4 reviews. See what others have said about Plaquenil, including the effectiveness, ease of use and side effects. Plaquenil Reviews Everyday Health. Taking Plaquenil for Rheumatoid Arthritis. Bad Side Effects of Plaquenil -. Apr 10, 2019 You should not use Plaquenil if you are allergic to hydroxychloroquine. Plaquenil should not be used for long-term treatment in children. To make sure Plaquenil is safe for you, tell your doctor if you have a history of vision changes or damage to your retina caused by an anti-malaria medication; Depending on what you're being treated for, it can take up to 6 months for the full benefits of Plaquenil hydroxychloroquine. Many people have nausea, stomach cramps, and diarrhea when they first start taking Plaquenil hydroxychloroquine. If you don't have to, don't stop your plaquenil. I stopped taking the plaquenil the beginning of December. It doesn't agree with my stomach I take it with meals too. And since I hadn't had a miraculous recovery the 6 months I'd been on it, I didn't think there was any harm in stopping it.