Please review the following URL and make sure that it is spelled correctly. Joint damage worries and aching hands are no fun, and if you’re experiencing those kinds of problems because of rheumatoid arthritis you may have options that can help you feel better. Mode of action of chloroquine Hydroxychloroquine brand name philippines Anita- I had always heard that too - that even if you stopped it, it would take a long time before it was out of your system. I still believe this to be true, but I am convinced now that plaquenil must have multiple modes of action, one being long term effects, and one being something happening in the short term. Hydroxychloroquine doesn’t work immediately. It may be 12 weeks or longer before you notice any benefit. Because it's a long-term treatment it's important to keep taking hydroxychloroquine unless you have severe side-effects It took about three months before I noticed any difference. Your RD should have told you it would take a while for it to be effective. If you are in a lot of pain, call your doctor and ask for a short round of prednisone. It will help you get through the rough patch until the Plaquneil kicks in. The progression of RA may be diminished in severity and duration by the combination of medicines and therapy that work best as determined by you and your physician. There’s no cure for arthritis, which is unfortunate, but feeling better is definitely possible. How long til hydroxychloroquine to work Hydroxychloroquine Plaquenil for Cicatricial Alopecia., Hydroxychloroquine Side-effects, uses, time to work Plaquenil and coumadin interaction The aforementioned rare side effect that affects vision hydroxychloroquine retinopathy, if caught early, may improve after discontinuation of Plaquenil. Since the side effect of vision loss is possible but rare, it is important for you to tell your doctor about any vision changes that you experience. Taking Plaquenil for Rheumatoid Arthritis. Bone Joint Muscle - Arthritis Plaquenil - How long till it.. How long did Plaquenil/Hydroxychloroquine take? DailyStrength. Typical starting dose is 800 mg. This is followed by 400 mg three times 6 hours after the first dose, 24 hours after the first dose, and 48 hours after the first dose. Find patient medical information for Hydroxychloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Well, about 2 weeks into my "stop" program, I suddenly realized it was helping me. It was so gradual that until I stopped, I didn't realize that I wasn't as tired all the time. I didn't ache quite so much, and my eyes and mouth weren't as dry. I started back up and it took me about a month to 2 months to get back on track.