Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take hydroxychloroquine with all of your drugs and health problems. Plaquenil toxicity symptoms liver Hydroxychloroquine for lyme arhtritis Compare Methotrexate vs Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Methotrexate rated 6.7/10 vs Plaquenil rated 6.8/10 in overall patient satisfaction. Hydroxychloroquine brand namePlaquenil is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. 1,2 We compare the side effects and drug effectiveness of Plaquenil and Methotrexate. The study is created by eHealthMe based on reports of 385,604 people who take Plaquenil and Methotrexate, and is updated regularly. eHealthMe has been monitoring drugs since 2008. Our original studies are referenced on 600+ peer-reviewed medical publications. For all uses of hydroxychloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. Methotrexate plaquenil alcohol Can I take Plaquenil and drink alcohol? - Page 6, Treatments for Rheumatoid Arthritis Pka of chloroquine Answer. In the US, we generally recommend no more than 2 glasses of alcoholic beverages per week. Two is okay as long as the treating rheumatologist or internist is monitoring the liver tests, and as long as the patient does not have any underlying liver disease such as hepatitis C, hemochromatosis. Alcohol with Methotrexate, Celebrex and Paquenil • Johns.. Plaquenil vs. Methotrexate side effect and effectiveness comparison.. Does anyone take methotrexate and hydroxychloroquine. - NRAS. I went on 15mg methotrexate per week and 400mg plaquenil per day. Within 6 weeks all symptoms were gone, returning only twice when I was having non-related health issues that challenged my immune system. Never had drug side effects except occasional nausea; my hair has thinned but I'm in my 60's so its to be expected. Risks Methotrexate most commonly causes nausea. Other common side effects include swollen gums, mouth sores and excess tiredness. Women who want to become pregnant should not take methotrexate. Methotrexate can cause an increase in liver enzymes and is therefore not recommended for those who drink alcohol. Hydroxychloroquine is a prescription drug. It comes as an oral tablet. Hydroxychloroquine is available as the brand-name drug Plaquenil. It’s also available in a generic version.