Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Chloroquine effect on gametocytes Plaquenil help dry eyes Plaquenil drug nutrient interactions Plaquenil and surgery Cannabidiol in the Cytochrome P-450 System. Cannabidiol can inhibit the cytochrome P450 system’s ability to metabolize certain drugs, leading to an overall increase in processing times. Interestingly, CBD oil is not alone in its effect on drug metabolism. Hydroxychloroquine is used in the treatment of malaria, rheumatic disorders, and systemic lupus erythematosus. 8 Many side effects have been reported associated with the use of hydroxychloroquine. Among these side effects, there is a particular concern regarding the development of cardiomyopathy and thrombocytopenia. 9,10 I was diagnosed with Lupus in 2002 and I have been on Plaquenil since then. Lupus, Fibromyalgia and Cymbalta - Lupus. and the Lyrica and Topamax work on the. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil and topamax Hydroxychloroquine Side Effects Common, Severe, Long Term., A case of thrombocytopenia associated with the use of. Plaquenil toxicity eyeChloroquine phosphate indicationsChloroquine protein degradationWithdrawal effects of plaquenilLong term chloroquine prophylaxis Drug-induced nail disease is diagnosed when a medication affects nail growth or structure. Drugs may cause Changes to the shape of the nail nail deformity Changes in the texture or composition of the nail nail dystrophy Abnormality of the tissues around the nail paronychia Pigmentation of the nail plate. Drug-induced nail disease DermNet NZ. Lupus, Fibromyalgia and Cymbalta - Lupus - Inspire. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Topiramate Topamax is a sulfamate-substituted monosaccharide oral anticonvulsant used for the treatment of seizures, prophylaxis for migraine, as well as off-label in the treatment of bipolar disorder. Since 2001, several case reports have described induced myopia and bilateral angle-closure glaucoma associated with topiramate use. 6 There is no known interaction between Plaquenil and Topamax in our records. However, an interaction may still exist. However, an interaction may still exist. Always consult your doctor before taking these medications together.