Weakness, swelling, and pain are the most common myositis symptoms. Myositis causes include infection, injury, autoimmune conditions, and drug side effects. How to reverse the side gastrointestinal side effects of plaquenil Hydroxychloroquine eye exam frequency Plaquenil liver kidney toxicity Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, headache, Muscle weakness also may be a side effect of certain drugs used to treat lupus and related conditions, including prednisone and other corticosteroids, cholesterol-lowering drugs and hydroxychloroquine Plaquenil®. Therefore, drug-induced muscle disease should be ruled out as a cause of weakness if you are taking any of these medications, as drug-induced muscle weakness usually does not produce elevated levels of muscle enzymes as is seen in lupus myositis. A drug-induced, or toxic, myopathy is defined as the acute or subacute manifestation of myopathic symptoms such as muscle weakness, myalgia, creatine kinase elevation, or myoglobinuria that can occur in patients without muscle disease when they are exposed to certain drugs. Myositis is caused by any condition that leads to inflammation in the muscles. Treatment of myositis varies according to the cause. Plaquenil for dermatomyositis muscle weakness Myositis Skin Care and Treatment The Myositis Association, How Lupus Affects the Muscles, Tendons and Joints Lupus. Hydroxychloroquine nursing implicationsHydroxychloroquine dosingPlaquenil medication for arthritis Myositis disease have specific patterns of weakness. There are 3 main types of myositis, dermatomyositis, polymyositis and inclusion body myositis. Both DM and PM are characterized by usually pronounced weakness of the proximal muscles. Those around the hip and shoulder girdles. Some cases eventually involve a muscle wasting process but not all. Myositis / muscle weakness -. Drug-related Myopathies of Which the Clinician Should Be Aware. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Injury. Vigorous exercise can lead to muscle pain, swelling, and weakness for hours or days after a workout. Inflammation contributes to these symptoms, technically making this a form of myositis. Myositis symptoms after exercise or injury nearly always resolve completely with rest and recovery. Treatment is similar to that for the muscle disease polymyositis. Avoidance of sun exposure during peak hours and use of sunblock and protective clothing are recommended to avoid exacerbating the skin aspects of the disease. Children with dermatomyositis are treated with the same medications and therapies as adults. Plaquenil hydroxychloroquine "I have dermatomyositis and have been taken Prednisone and Plaquenil. At first the combo was helping with the muscle pain and rash. After 2 wks on the Plaquenil I got a sunburn itchy rash all over my body. I also have bruise/like spots where the old rash was."