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Definition of antabuse

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    Definition of antabuse


    Disulfiram (sold under the trade names Antabuse and Antabus) is a drug used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). Disulfiram works by inhibiting the enzyme acetaldehyde dehydrogenase, which means that many of the effects of a "hangover" are felt immediately after alcohol is consumed. "Disulfiram plus alcohol, even small amounts, produce flushing, throbbing in head and neck, throbbing headache, respiratory difficulty, nausea, copious vomiting, sweating, thirst, chest pain, palpitation, dyspnea, hyperventilation, tachycardia, hypotension, syncope, marked uneasiness, weakness, vertigo, blurred vision, and confusion. In severe reactions there may be respiratory depression, cardiovascular collapse, arrhythmias, myocardial infarction, acute congestive heart failure, unconsciousness, convulsions, and death." In the body, alcohol is converted to acetaldehyde, which is then broken down by acetaldehyde dehydrogenase. If the dehydrogenase enzyme is inhibited, acetaldehyde builds up and causes unpleasant effects. Disulfiram should be used in conjunction with counseling and support. Disulfiram has been studied as a possible treatment for cancer Under normal metabolism, alcohol is broken down in the liver by the enzyme alcohol dehydrogenase to acetaldehyde, which is then converted by the enzyme acetaldehyde dehydrogenase to a harmless acetic acid derivative (acetyl coenzyme A). azithromycin for std A drug sometimes used in the management of alcoholism, which causes severe nausea and vomiting, sweating, breathlessness, headache and chest pain if any alcohol is taken after it has been given. Disulfiram inhibits the enzyme aldehyde dehydrogenase that breaks down acetaldehyde, a toxic metabolite of alcohol, so that this accumulates. The method is a form of aversion therapy and is not without danger of collapse and death from the toxic effects.

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    Disulfiram (tetraethylthiuramdisulfide) was accidentally discovered to combine with ethyl alcohol to produce a noxious effect by Jacobsen and Hald, in Denmark, in 1947. After its therapeutic introduction by Martensen-Larsen in 1948, this chemical compound, with the market name of Antabuse, has been used in the treatment of patients suffering from chronic alcoholism in unknown numbers of thousands. As with any new treatment method, an overly enthusiastic reception occurred, with successes reported in 60% to 80% of the patients so treated and followed for six months to a year. However, the enthusiasm has diminished, until now the recovery rates are about the same as those reported for other therapeutic modalities. Unfortunately, rather than helping those who did not benefit from other techniques, disulfiram works best with those patients who generally do better with any type of treatment. Unlike the other modal verbs, it is only found in the past tense. Therefore, when it is used with do to make negatives and questions, the form of the auxil...

    Definition of antabuse

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    Disulfiram - a drug trade name Antabuse used in the treatment of alcoholism; causes nausea and vomiting if alcohol is ingested. Antabuse. medicament, medication, medicinal drug, medicine - medicine something that treats or prevents or alleviates the symptoms of disease. Translations. zoloft uses N a drug trade name Antabuse used in the treatment of alcoholism; causes nausea and vomiting if alcohol is ingested. medicine something that treats or prevents or alleviates the symptoms of disease. Antabuse Definition Of Science LocalPharmacy Prices for Generic Viagra Online! Best prices on Levitra from licensed, top-rated pharmacies in the U. S. Canada, and internationally. Buy Generic Cialis Online.

     
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